When Jeanne started taking Zepbound, a popular weight-loss drug, she expected physical changes. What she didn’t anticipate was how it would shake up her 15-year marriage to Javier. The drug, which has been hailed as a “miracle” for some, not only helped Jeanne shed 60 pounds but also transformed their relationship in ways neither saw coming.

For Javier, the changes were bittersweet. He missed the physical closeness they once shared. “I used to love feeling her body next to me in bed—the softness, the extra curves,” he shared. “That’s no longer an option.” The couple hasn’t been intimate since Jeanne started the medication, and they’re now navigating a new dynamic in their marriage.

This isn’t just their story. Experts point out that while weight-loss drugs like Zepbound come with physical side effects—nausea, headaches, and more—their impact on relationships is often overlooked. Studies, including one from 2018 on bariatric surgery, show that significant weight loss can strain partnerships. When one person changes dramatically, it can disrupt the balance in a relationship, forcing couples to reexamine what they value in each other.

Jeanne’s journey highlights a growing conversation about the ripple effects of these drugs. While they can be life-changing for individuals, they also challenge couples to adapt to a new normal. Whether it’s rekindling intimacy or finding new ways to connect, the path forward isn’t always straightforward.

So, while weight-loss drugs may transform bodies, they can also reshape relationships. For couples like Jeanne and Javier, it’s a journey of adjustment, understanding, and rediscovery.